Lo Re G, Galia M, La Grutta L, Russo S, Runza G, Taibbi A, D'Agostino T, Lo Greco V, Bartolotta T V, Midiri M, Cardinale A E, De Maria M, Lagalla R
Sezione di Scienze Radiologiche del Dipartimento di Biotecnologie Mediche e Medicina Legale, via del Vespro 127, Palermo, Italy.
Radiol Med. 2007 Dec;112(8):1173-87. doi: 10.1007/s11547-007-0214-9. Epub 2007 Dec 13.
This study was performed to evaluate the usefulness of digital cineradiography in detecting swallowing disorders in dysphagic patients affected by amyotrophic lateral sclerosis (ALS) with a view to planning an adequate therapeutic approach.
From January 2005 to September 2006, 23 patients (10 men and 13 women; mean age 41.3+/-8.6 years) affected by ALS were evaluated with digital cineradiography to assess the grade of dysphagia. All patients were classified using the Hillel ALS Severity Scale (ALSSS). All examinations were performed with radiocontrolled equipment provided with a digital C-arm.
The cineradiographic technique enabled us to differentiate patients with disorders of the oral (17/23) and/or pharyngeal (19/23) swallowing phase from those without swallowing dysfunction (4/23). In 14/23 patients, passage of contrast medium into the upper airways was observed during swallowing, whereas in 5/23 cases, aspiration of contrast medium into the lower airways was recorded.
The videofluoroscopic swallowing study has high diagnostic capabilities in the evaluation of swallowing disorders, as it is able to identify the degree and causes of impairment. In addition, the study proved useful for planning speech therapy and for follow-up in patients with ALS.
本研究旨在评估数字动态放射成像在检测肌萎缩侧索硬化症（ALS）所致吞咽困难患者吞咽障碍方面的效用，以期规划适当的治疗方法。
2005年1月至2006年9月，对23例受ALS影响的患者（10例男性和13例女性；平均年龄41.3±8.6岁）进行数字动态放射成像检查，以评估吞咽困难的程度。所有患者均使用希勒尔ALS严重程度量表（ALSSS）进行分类。所有检查均使用配备数字C形臂的放射控制设备进行。
动态放射成像技术使我们能够区分有口腔（17/23）和/或咽部（19/23）吞咽阶段障碍的患者与无吞咽功能障碍的患者（4/23）。在23例患者中的14例中，吞咽期间观察到造影剂进入上呼吸道，而在23例中的5例中，记录到造影剂吸入下呼吸道。
视频荧光吞咽研究在评估吞咽障碍方面具有很高的诊断能力，因为它能够识别损伤的程度和原因。此外，该研究被证明对规划言语治疗和ALS患者的随访有用。
