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一项针对宫颈涂片异常后接受阴道镜检查的女性焦虑和抑郁情况的2年随访研究。

A 2-year follow-up study of anxiety and depression in women referred for colposcopy after an abnormal cervical smear.

作者信息

Hellsten C, Sjöström K, Lindqvist P G

机构信息

Department of Obstetrics and Gynaecology, Malmö University Hospital, Lund University, Malmö, Sweden.

出版信息

BJOG. 2008 Jan;115(2):212-8. doi: 10.1111/j.1471-0528.2007.01609.x.

DOI:10.1111/j.1471-0528.2007.01609.x
PMID:18081601
Abstract

OBJECTIVES

The aim of this study was to determine if there were any long-lasting elevated anxiety levels in women attending colposcopy after an abnormal cervical smear.

DESIGN

Prospective study.

SETTING

Department of Obstetrics and Gynaecology, Malmö University Hospital, Sweden.

POPULATION

One hundred consecutive women were invited to participate when referred for colposcopy.

METHODS

Women in the study group completed the State-Trait Anxiety Inventory, the Montgomery-Asberg Depression Rating Scale-self-rate (MADRS-S) and had a psychosocial interview prior to colposcopy at their two follow-up visits.

MAIN OUTCOME MEASURES

State anxiety levels and depression scores at first visit, 6 months and 2 years.

RESULTS

At follow up, levels of state anxiety and the depression scores of the women studied had decreased and were comparable to those of Swedish normative data. Two variables from the MADRS-S, 'ability to focus on different activities' and 'emotional involvement with others and in activities' were the most prominent for women with moderate to severe depression. At the 2-year visit, 30% of the women still had a fear of cancer.

CONCLUSIONS

Referral for colposcopy after an abnormal cervical smear does not seem to result in long-lasting anxiety and depression. However, a subgroup of women, with the initially highest depression scores, still had at 2-year state anxiety levels and depression scores significantly higher than normal. Almost one-third of the women still had a fear of cancer in spite of lower 2-year state anxiety levels.

摘要

目的

本研究旨在确定宫颈涂片异常后接受阴道镜检查的女性是否存在长期焦虑水平升高的情况。

设计

前瞻性研究。

地点

瑞典马尔默大学医院妇产科。

研究对象

连续邀请100名因阴道镜检查前来就诊的女性参与研究。

方法

研究组女性在阴道镜检查前、两次随访时完成状态-特质焦虑量表、蒙哥马利-阿斯伯格抑郁评定量表自评版(MADRS-S),并接受社会心理访谈。

主要观察指标

首次就诊、6个月及2年时的状态焦虑水平和抑郁评分。

结果

随访时,研究中女性的状态焦虑水平和抑郁评分均有所下降,与瑞典正常数据相当。对于中度至重度抑郁的女性,MADRS-S中的两个变量“专注于不同活动的能力”和“与他人及活动的情感卷入”最为突出。在2年随访时,30%的女性仍对癌症存在恐惧。

结论

宫颈涂片异常后转诊接受阴道镜检查似乎不会导致长期焦虑和抑郁。然而,最初抑郁评分最高的一组女性在2年时的状态焦虑水平和抑郁评分仍显著高于正常水平。尽管2年时状态焦虑水平有所降低,但仍有近三分之一的女性对癌症存在恐惧。

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