西班牙欧洲野猪（Sus scrofa）戊型肝炎病毒感染的流行病学研究。
Epidemiological study of hepatitis E virus infection in European wild boars (Sus scrofa) in Spain.
作者信息
de Deus Nilsa, Peralta Bibiana, Pina Sonia, Allepuz Alberto, Mateu Enric, Vidal Dolors, Ruiz-Fons Francisco, Martín Marga, Gortázar Christian, Segalés Joaquim
机构信息
Centre de Recerca en Sanitat Animal, Esfera UAB, Edifici CReSA, Campus de Bellaterra, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain.
出版信息
Vet Microbiol. 2008 May 25;129(1-2):163-70. doi: 10.1016/j.vetmic.2007.11.002. Epub 2007 Nov 9.
Evidence of hepatitis E virus (HEV) infection in Spanish domestic pig has been reported and hence it was advisable to search for this zoonotic pathogen in wild boar populations. A total of 150 wild boar serum samples from eight geographic areas from South-Central Spain were used to investigate HEV infection in European wild boar (Sus scrofa) by means of serology and PCR and its distribution by age, region and management system. Anti-HEV IgG, IgM and IgA were determined by an in-house ELISA. The overall seroprevalence was 42.7% (range 30.63-55.65%) and 19.6% (range 13.53-27.40%) of the animals tested positive for HEV RNA. Wild boar sequences were clustered within the genotype 3. This is the first description of HEV infection in Spanish wild boar and the results obtained may suggest a possible role of wild boar as a HEV reservoir for both domestic animals and humans.
西班牙家猪感染戊型肝炎病毒（HEV）的证据已有报道，因此有必要在野猪种群中寻找这种人畜共患病原体。本研究采集了来自西班牙中南部八个地理区域的150份野猪血清样本，采用血清学和PCR方法调查欧洲野猪（Sus scrofa）的HEV感染情况，并分析其在年龄、地区和管理系统方面的分布。通过内部ELISA法检测抗HEV IgG、IgM和IgA。总体血清阳性率为42.7%（范围30.63 - 55.65%），19.6%（范围13.53 - 27.40%）的动物HEV RNA检测呈阳性。野猪序列聚类于3型。这是西班牙野猪感染HEV的首次描述，所得结果可能表明野猪可能作为家畜和人类的HEV宿主。
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