Mazzaglia Peter J, Berber Eren, Siperstein Allan E
Department of Surgery A-80, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH, USA.
Curr Treat Options Oncol. 2007 Aug;8(4):322-30. doi: 10.1007/s11864-007-0038-9.
In our armamentarium against neuroendocrine hepatic metastases, radiofrequency thermal ablation has proven to play a valuable role. Patients with neuroendocrine malignancies that progress to hepatic metastases may suffer not only from the hormonal sequelae of their disease, but also face the specter of death within several years from progressive hepatic replacement. For the majority of these patients who are not surgical candidates due to the extent of liver involvement, radiofrequency thermal ablation represents a low-risk treatment modality effective at both symptom alleviation and survival prolongation. Utilizing a laparoscopic approach guided by intra-operative ultrasound, effective tumor ablation can be achieved with minimal morbidity and low rates of local tumor recurrence.
在我们对抗神经内分泌性肝转移的手段中，射频热消融已证明发挥着重要作用。神经内分泌恶性肿瘤进展为肝转移的患者不仅可能遭受疾病的激素后遗症，还可能面临因肝脏进行性替代在数年内死亡的威胁。对于大多数因肝脏受累范围而不适合手术的患者，射频热消融是一种低风险的治疗方式，对缓解症状和延长生存期均有效。采用术中超声引导的腹腔镜方法，可实现有效的肿瘤消融，且发病率极低，局部肿瘤复发率也低。
