Nishiura Motoko, Johkoh Takeshi, Yamamoto Shuji, Honda Osamu, Kozuka Takenori, Koyama Mitsuhiro, Tomiyama Noriyuki, Hamada Seiki, Murakami Takamichi, Matsumoto Takashi, Narumi Yoshifumi, Nakamura Hironobu
Division of Health Science, Osaka University Graduate School of Medicine, Suita, Japan.
Radiat Med. 2007 Dec;25(10):523-8. doi: 10.1007/s11604-007-0179-6. Epub 2007 Dec 25.
The aim of this study was to evaluate the decreasing of cardiac motion artifact and whether the extent of ground-glass attenuation of idiopathic pulmonary fibrosis (IPF) was accurately assessed by electrocardiography (ECG)-triggered high-resolution computed tomography (HRCT) by 0.5-s/rotation multidetector-row CT (MDCT).
ECG-triggered HRCT were scanned at the end-diastolic phase by a MDCT scanner with the following scan parameters; axial four-slice mode, 0.5 mm collimation, 0.5-s/rotation, 120 kVp, 200 mA/rotation, high-frequency algorithm, and half reconstruction. In 42 patients with IPF, both conventional HRCT (ECG gating(-), full reconstruction) and ECG-triggered HRCT were performed at the same levels (10-mm intervals) with the above scan parameters. The correlation between percent diffusion of carbon monoxide of the lung (%DLCO) and the mean extent of ground-glass attenuation on both conventional HRCT and ECG-triggered HRCT was evaluated with the Spearman rank correlation coefficient test.
The correlation between %DLCO and the mean extent of ground-glass attenuation on ECG-triggered HRCT (observer A: r = -0.790, P < 0.0001; observer B: r = -0.710, P < 0.0001) was superior to that on conventional HRCT (observer A: r = -0.395, P < 0.05; observer B: r = -0.577, P = 0.002) for both observers.
ECG-triggered HRCT by 0.5 s/rotation MDCT can reduce the cardiac motion artifact and is useful for evaluating the extent of ground-glass attenuation of IPF.