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[尿酸与动脉高血压。III. 硝苯地平对原发性动脉高血压患者血清尿酸水平及其肾脏排泄的影响]

[Uric acid and arterial hypertension. III. Effect of nifedipine on serum uric acid level and its renal excretion in primary arterial hypertension].

作者信息

Tykarski A

机构信息

Kliniki Nadciśnienia Tetniczego Instytutu Kardiologii AM w Poznaniu.

出版信息

Pol Arch Med Wewn. 1991 Sep;86(3):177-82.

PMID:1808602
Abstract

In sixteen patients with moderate essential hypertension the effects of 10-day nifedipine treatment on serum uric acid and renal excretion of uric acid were evaluated. Neither serum uric acid nor clearance and fractional excretion of uric acid changed significantly during treatment with nifedipine. Positive correlation between fall in systolic arterial pressure and decrease of serum uric acid in hypertensive patients treated with nifedipine was found.

摘要

对16例中度原发性高血压患者，评估了硝苯地平治疗10天对血清尿酸及尿酸肾排泄的影响。在硝苯地平治疗期间，血清尿酸、尿酸清除率及尿酸排泄分数均无显著变化。发现硝苯地平治疗的高血压患者收缩压下降与血清尿酸降低之间呈正相关。

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