Mehrabi Mehran, Allen John M, Roser Steven M
Division of Oral and Maxillofacial Surgery, Emory University School of Medicine, 1365-B Clifton Road NE, Suite 2300-B, Atlanta, GA 30322, USA.
Oral Maxillofac Surg Clin North Am. 2007 Feb;19(1):69-84, vi. doi: 10.1016/j.coms.2006.11.010.
Surgical extraction of third molars is one of the most common of all surgical procedures. The outcome of third molar surgery includes pain, trismus, edema, nausea, infection, and alveolar osteitis. The intent of this article is to provide a literature review and analysis of the various chemotherapeutic agents used to control, minimize, or eliminate these outcomes. Unfortunately, comparison of the published studies represents a tremendous challenge because of the variability in parameters and methods used for each study. A trend does exist among many of the current researchers, who realize that randomized, controlled, evidence-based research rather than personal experience is necessary to develop appropriate guidelines for using chemotherapeutic agents.
第三磨牙的外科拔除是所有外科手术中最常见的手术之一。第三磨牙手术的结果包括疼痛、牙关紧闭、水肿、恶心、感染和干槽症。本文旨在对用于控制、最小化或消除这些结果的各种化疗药物进行文献综述和分析。不幸的是，由于每项研究所用参数和方法的差异，对已发表研究进行比较是一项巨大的挑战。目前许多研究人员确实存在一种趋势，他们意识到需要进行随机、对照、循证研究而非个人经验，才能制定出使用化疗药物的适当指南。
