Vignoles P, Dreyfuss G, Rondelaud D
Faculté de pharmacie, laboratoire de parasitologie, Limoges, France.
Ann Rech Vet. 1991;22(4):359-63.
The toxicity of benzamido-2-nitro-5-thiazole (BNT) and 3 derivatives was studied on Lymnaea peregra ovata and Gammarus pulex pulex. These results were compared with the toxicity obtained by application of a basic product, niclosamide. The evaluation of LC50 (50% lethality concentration) was studied to evaluate the toxicity of each product after 4 different assay periods: 24, 48, 72 and 96 h. The compounds had a high toxicity against snails. Molluscicidal effect was higher than the lethal activity against Crustacea. The ortho substitution decreased the toxicity of products compared with BNT.