Jin Wei, Du Jin-kui, Yuan Yi, Wei Feng-hua, Liu Wei, Wang Hui, Li Gui-ling, Xu Xing-jian
Department of Chemistry and Chemical Industry, Huazhong University of Science and Technology, Wuhan 430030, China.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2007 Oct;25(5):411-4.
To observe the molluscicidal effect of chlorosalicylicamide on Oncomelania hupensis and toxicity on fishes.
Different concentrations of chlorosalicylicamide were prepared, and immersion and spraying methods were used to test its molluscicidal effect and toxicity to fishes. Niclosamide ethanolamine salt was used as control.
Under water temperature of 28 C with the dose of chlorosalicylicamide at 0.25 mg/L and 0.4 mg/L, the mortality rate of snails by immersion was 97.8% and 100% respectively after 48 h, and the LC50 was 0.0674 mg/L. While for niclosamide at the same doses, the mortality rate of snails was 22.2% and 66.7% respectively, and the LC50 was 0.397 6 mg/L. With the concentration of 0.4 mg/L for 72 h, the fish death rate in chlorosalicylicamide and niclosamide was 50.0% and 100% respectively.
Chlorosalicylicamide shows a molluscicidal effect on Oncomelania snails and a lower toxicity to fishes than that of niclosamide.
观察氯水杨酸酰胺对钉螺的杀螺效果及对鱼类的毒性。
配制不同浓度的氯水杨酸酰胺，采用浸杀法和喷洒法检测其杀螺效果及对鱼类的毒性，以氯硝柳胺乙醇胺盐作为对照。
水温28℃时，氯水杨酸酰胺剂量为0.25mg/L和0.4mg/L，浸杀48h后钉螺死亡率分别为97.8%和100%，LC50为0.0674mg/L；相同剂量的氯硝柳胺浸杀钉螺死亡率分别为22.2%和66.7%，LC50为0.3976mg/L。浓度为0.4mg/L作用72h，氯水杨酸酰胺组和氯硝柳胺组鱼类死亡率分别为50.0%和100%。
氯水杨酸酰胺对钉螺有杀螺效果，对鱼类的毒性低于氯硝柳胺。
