组织相容性类型和病毒抗体。

Histocompatibility types and viral antibodies.

作者信息

Lehrich J R, Arnason B G

出版信息

Arch Neurol. 1976 Jun;33(6):404-5. doi: 10.1001/archneur.1976.00500060010003.

DOI:10.1001/archneur.1976.00500060010003

Abstract

Serum neutralizing (Nt) antibodies to herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), and histocompatibility (HL-A) types, were determined in multiple sclerosis (MS) patients and in control subjects. Titers of Nt antibodies to HSV-1 and to HSV-2 were increased among subjects bearing HL-A3 or HL-A7 or both, whether they suffered from MS or not. The increases were statistically significant in the MS group. The MS and control groups did not differ significantly in levels of HSV-1 or HSV-2 Nt antibodies.

摘要

对1型单纯疱疹病毒（HSV-1）和2型单纯疱疹病毒（HSV-2）的血清中和（Nt）抗体以及组织相容性（HL-A）类型，在多发性硬化症（MS）患者和对照受试者中进行了测定。携带HL-A3或HL-A7或两者的受试者中，无论是否患有MS，HSV-1和HSV-2的Nt抗体滴度均升高。在MS组中，这种升高具有统计学意义。MS组和对照组在HSV-1或HSV-2 Nt抗体水平上没有显著差异。