Gregory Cria O, Corvalán Camila, Ramirez-Zea Manuel, Martorell Reynaldo, Stein Aryeh D
Nutrition and Health Sciences Program, Graduate Division of Biological and Biomedical Sciences, Emory University, Atlanta, GA, USA.
Public Health Nutr. 2008 Oct;11(10):1037-45. doi: 10.1017/S1368980007001504. Epub 2007 Dec 20.
BMI and waist circumference (WC) are used to screen for cardio-metabolic risk; however it is unclear how well these indices perform in populations subject to childhood stunting.
To evaluate BMI and WC as indicators of cardio-metabolic risk and to determine optimal cut-off points among 1,325 Guatemalan adults (44 % stunted: 162 cm men).
Cardio-metabolic risk factors were systolic/diastolic blood pressure 85 mmHg, glucose 5 mmol/l, TAG 7 mmol/l, ratio of total cholesterol to HDL-cholesterol 0, and the presence of two or more and three or more of the preceding risk factors. Receiver operating characteristic (ROC) curve analysis was used.
Areas under the ROC curve were in the range of 005978 for WC among men and 006472 among women, respectively. Optimal cut-off points for BMI were 242651 kg/m2 stunted; 242656 kg/m2 among women (262769 kg/m2 non-stunted). Optimal cut-off points for WC were 879134 cm stunted; 889333 cm among women (909486 cm non-stunted).
Optimal cut-off points for BMI were slightly higher among women than men with no meaningful differences by stature. Optimal cut-off points for WC were several centimetres lower for stunted compared with non-stunted men, and both were substantially lower than the current recommendations among Western populations. Cut-off points derived from Western populations may not be appropriate for developing countries with a high prevalence of stunting.
体重指数(BMI)和腰围(WC)用于筛查心血管代谢风险;然而,这些指标在受儿童期发育迟缓影响的人群中的表现尚不清楚。
评估BMI和WC作为心血管代谢风险指标,并确定1325名危地马拉成年人(44%发育迟缓:男性身高162厘米)中的最佳切点。
心血管代谢风险因素包括收缩压/舒张压≥85 mmHg、血糖≥5 mmol/l、甘油三酯(TAG)≥7 mmol/l、总胆固醇与高密度脂蛋白胆固醇之比≥0,以及存在两种或更多及三种或更多上述风险因素。采用受试者工作特征(ROC)曲线分析。
男性中WC的ROC曲线下面积分别为0.05978,女性为0.06472。发育迟缓男性的BMI最佳切点为24.2651 kg/m²;女性为24.2656 kg/m²(非发育迟缓女性为26.2769 kg/m²)。发育迟缓男性的WC最佳切点为87.9134 cm;女性为88.9333 cm(非发育迟缓女性为90.9486 cm)。
女性的BMI最佳切点略高于男性,按身高无显著差异。发育迟缓男性的WC最佳切点比非发育迟缓男性低几厘米,且两者均远低于西方人群目前的建议值。源自西方人群的切点可能不适用于发育迟缓患病率高的发展中国家。