Kiagova A A, Ismailova M I, Potapenko A Ia
Biofizika. 1991 Nov-Dec;36(6):1061-3.
Psoralen sensitized photodamage of rat peritoneal exudate cells was investigated. Irradiation of cells induced latent lesions in membranes which during thermal activation at the post-irradiation stage were transformed into permeability channels for trypan blue. The effect linearly increased with fluence of irradiation which indicates one hit production of thermolabile psoralen photoproducts in the membranes.
研究了补骨脂素致敏的大鼠腹腔渗出细胞的光损伤。细胞照射诱导了膜中的潜在损伤，在照射后阶段的热激活过程中，这些损伤转化为锥虫蓝的通透性通道。该效应随照射通量线性增加，这表明膜中热敏性补骨脂素光产物的产生为单打击过程。
