Saba Luca, Mallarini Giorgio
Department of Science of the Images, Policlinico Universitario, s.s. 554 Monserrato, Cagliari 09045, Italy.
AJR Am J Roentgenol. 2008 Jan;190(1):W41-6. doi: 10.2214/AJR.07.2604.
Atherosclerotic disease of the carotid arteries is one of the most important causes of stroke. Our objective was to evaluate the interobserver agreement in the measurement of the degree of carotid plaque stenosis by using MDCT angiography (MDCTA) and the effects produced using different window parameters and by the different types of plaque.
From June 2005 to June 2006, we retrospectively evaluated 215 patients (151 men, 64 women) who underwent MDCTA for the study of carotid arteries. In all patients we measured degree of stenosis, applying the criteria of the North American Symptomatic Carotid Endarterectomy Trial (NASCET). Each patient was studied independently by two observers. We used three window settings for the measurements. We grouped the measurements according to the type of plaque. Obtained data were then analyzed to calculate the interobserver agreement and the kappa value.
Kappa values for the degree of stenosis evaluation were 0.696, 0.79, and 0.775 for window settings 1, 2, and 3, respectively. The best agreement was observed in the assessment of fatty plaque, whereas the presence of calcification produced disagreement.
We observed a very good interobserver agreement in the evaluation of degree of stenosis using MDCTA with the application of specific visualization parameters. Our data suggested that MDCTA can provide reproducible values.
颈动脉粥样硬化疾病是中风的最重要病因之一。我们的目的是评估使用多层螺旋CT血管造影(MDCTA)测量颈动脉斑块狭窄程度时观察者间的一致性,以及不同窗宽参数和不同类型斑块所产生的影响。
2005年6月至2006年6月,我们回顾性评估了215例接受MDCTA检查以研究颈动脉的患者(151例男性,64例女性)。对所有患者应用北美症状性颈动脉内膜切除术试验(NASCET)的标准测量狭窄程度。由两名观察者分别独立研究每位患者。测量时我们使用了三种窗宽设置。我们根据斑块类型对测量结果进行分组。然后对获得的数据进行分析以计算观察者间的一致性和kappa值。
窗宽设置1、2和3评估狭窄程度的kappa值分别为0.696、0.79和0.775。在评估脂肪斑块时观察到最佳一致性,而钙化的存在则导致了不一致。
我们观察到在使用MDCTA并应用特定的可视化参数评估狭窄程度时,观察者间具有很好的一致性。我们的数据表明MDCTA可以提供可重复的值。