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糖组学前沿:疾病中的生物信息学与生物标志物。一份由美国国立卫生研究院校园(马里兰州贝塞斯达,2006年9月11日至13日)研讨会上焦点小组讨论整理而成的美国国立卫生研究院白皮书。

Frontiers in glycomics: bioinformatics and biomarkers in disease. An NIH white paper prepared from discussions by the focus groups at a workshop on the NIH campus, Bethesda MD (September 11-13, 2006).

作者信息

Packer Nicolle H, von der Lieth Claus-Wilhelm, Aoki-Kinoshita Kiyoko F, Lebrilla Carlito B, Paulson James C, Raman Rahul, Rudd Pauline, Sasisekharan Ram, Taniguchi Naoyuki, York William S

机构信息

Macquarie University, Sydney, New South Wales, NSW 2109, Australia.

出版信息

Proteomics. 2008 Jan;8(1):8-20. doi: 10.1002/pmic.200700917.

Abstract

Key issues relating to glycomics research were discussed after the workshop entitled "Frontiers in Glycomics: Bioinformatics and Biomarkers in Disease" by two focus groups nominated by the organizers. The groups focused on two themes: (i) glycomics as the new frontier for the discovery of biomarkers of disease and (ii) requirements for the development of informatics for glycomics and glycobiology. The mandate of the focus groups was to build consensus on these issues and develop a summary of findings and recommendations for presentation to the NIH and the greater scientific community. A list of scientific priorities was developed, presented, and discussed at the workshops. Additional suggestions were solicited from workshop participants and collected using the workshop mailing list. The results are summarized in this White Paper, authored by the co-chairs of the focus groups.

摘要

在名为“糖组学前沿:疾病中的生物信息学与生物标志物”的研讨会之后,由组织者提名的两个焦点小组讨论了与糖组学研究相关的关键问题。这些小组聚焦于两个主题:(i)糖组学作为疾病生物标志物发现的新前沿;(ii)糖组学和糖生物学信息学开发的要求。焦点小组的任务是就这些问题达成共识,并总结研究结果和建议,以便提交给美国国立卫生研究院(NIH)和更广泛的科学界。在研讨会上制定、展示并讨论了一份科学优先事项清单。还通过研讨会邮件列表向研讨会参与者征求了其他建议并进行了收集。本白皮书由焦点小组联合主席撰写,总结了相关结果。

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