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营养状况:血液学与白蛋白。欧洲营养与衰老研究协作网(Euronut SENECA)研究者

Nutritional status: haematology and albumin. Euronut SENECA investigators.

作者信息

Dirren H, Decarli B, Lesourd B, Schlienger J L, Deslypere J P, Kiepurski A

出版信息

Eur J Clin Nutr. 1991 Dec;45 Suppl 3:43-52.

PMID:1809568
Abstract

In the context of the Euronut SENECA study of nutrition and the elderly, performed in 19 towns situated in 12 European countries, blood haemoglobin and haematocrit, and serum albumin were measured in a large sample of 70-75-year-old subjects. The mean haemoglobin (Hb) values for the different towns ranged from 144 g l-1 to 157 g l-1 for men and from 131 g l-1 to 150 g l-1 for women. The town haematocrit (Hct) means ranged from 43.0% to 48.9% for men and from 39.7% to 46.4% for women. No clear geographical pattern emerged for either Hb or Hct. The 95% ranges (2.5-97.5 percentile intervals) for Hb and Hct for all towns combined (without any claim of being representative of Europe) were very similar to those reported in the NHANES II study of the USA. Prevalences of anaemia, using the WHO definition (Hb less than 130 g l-1 for men and Hb less than 120 g l-1 for women) were 5.2% for men and 5.7% for women. The town mean serum albumins ranged from 40.3 g l-1 to 44.3 g l-1 for men and from 40.3 g l-1 to 43.2 g l-1 for women. No clear geographical pattern emerged. Mean values were somewhat lower than for younger adults and comparable to other published data. Most albumin values were in the normal range, with only 2.0% of both men and women having levels below 35 g l-1 and only 0.4% of men and no women having levels below 30 g l-1. These results show that these 70-75-year-old subjects who chose to participate in the study were in relatively good health as judged from their haemoglobin, haematocrit and serum albumin levels.

摘要

在欧洲营养与老年人研究(Euronut SENECA)项目中,研究人员在位于12个欧洲国家的19个城镇开展了研究,对大量70至75岁的受试者进行了血红蛋白、血细胞比容以及血清白蛋白的检测。不同城镇男性的平均血红蛋白(Hb)值在144克/升至157克/升之间,女性的平均血红蛋白值在131克/升至150克/升之间。城镇男性的血细胞比容(Hct)平均值在43.0%至48.9%之间,女性的血细胞比容平均值在39.7%至46.4%之间。无论是Hb还是Hct,均未呈现出明显的地理分布模式。所有城镇合并后的Hb和Hct的95%范围(第2.5至97.5百分位数区间)(并不声称具有欧洲代表性)与美国国家健康与营养检查调查(NHANES II)研究报告的范围非常相似。按照世界卫生组织的定义(男性Hb低于130克/升,女性Hb低于120克/升),男性贫血患病率为5.2%,女性贫血患病率为5.7%。城镇男性血清白蛋白平均值在40.3克/升至44.3克/升之间,女性血清白蛋白平均值在40.3克/升至43.2克/升之间。未呈现出明显的地理分布模式。平均值略低于年轻成年人,与其他已发表数据相当。大多数白蛋白值处于正常范围,男性和女性仅有2.0%的水平低于35克/升,男性仅有0.4%的水平低于30克/升,女性则无此情况。这些结果表明,从血红蛋白、血细胞比容和血清白蛋白水平判断,这些选择参与研究的70至75岁受试者健康状况相对良好。

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