Haller J, Löwik M R, Ferry M, Ferro-Luzzi A
Eur J Clin Nutr. 1991 Dec;45 Suppl 3:63-82.
This chapter describes the vitamin plasma concentration data collection, preliminary analysis and results of the Euronut SENECA study. Blood plasma was collected from approximately 2500 elderly subjects born in 1913-1918 living in 17 small towns in 11 European countries, and the plasma levels of carotene, retinol, alpha-tocopherol, vitamin B12, folic acid and pyridoxal 5'-phosphate were determined. There were very large within- and between-centre differences in vitamin levels with no definite geographical pattern emerging. The vitamin status for retinol and folic acid was adequate in all centres. The prevalence of biochemical vitamin B6 deficiency was widespread and reached over 50% in some centres. Vitamin B12 biochemical deficiency was limited to ten centres and its prevalence was 1.6%-10%. Vitamin E biochemical deficiency was found in seven centres and varied from 0.5% to 25%.
本章描述了欧洲营养老年人群心血管疾病合作研究（Euronut SENECA）中维生素血浆浓度数据的收集、初步分析及结果。研究从生活在11个欧洲国家17个小镇的约2500名出生于1913年至1918年的老年人中采集了血浆，并测定了血浆中胡萝卜素、视黄醇、α-生育酚、维生素B12、叶酸和5'-磷酸吡哆醛的水平。维生素水平在各中心内部和中心之间存在非常大的差异，未呈现出明确的地理模式。所有中心的视黄醇和叶酸维生素状态充足。生化性维生素B6缺乏普遍存在，在一些中心超过50%。维生素B12生化缺乏仅限于10个中心，其患病率为1.6%至10%。在7个中心发现了维生素E生化缺乏，其范围从0.5%至25%不等。
