血管紧张素转换酶催化血管紧张素III的形成。
Formation of angiotensin III by angiotensin-converting enzyme.
作者信息
Chiu A T, Ryan J W, Stewart J M, Dorer F E
出版信息
Biochem J. 1976 Apr 1;155(1):189-92. doi: 10.1042/bj1550189.
Abstract
Angiotensin III is formed from des-Asp1 -angiotensin I by angiotensin-converting enzyme. The Km (11 muM) of the reaction is one-third of that for the conversion of angiotensin I into angiotensin II. As suggested by the Km values, bradykinin, peptide BPP9a and angiotensins II and III are better inhibitors of the formation of angiotensin II than of the formation of angiotensin III.
摘要
血管紧张素III由血管紧张素转换酶作用于去天门冬氨酸-血管紧张素I生成。该反应的米氏常数（Km）为11微摩尔，是血管紧张素I转化为血管紧张素II反应米氏常数的三分之一。正如米氏常数所示，缓激肽、肽BPP9a以及血管紧张素II和III对血管紧张素II生成的抑制作用比对血管紧张素III生成的抑制作用更强。
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