两种新生儿低血糖筛查方法的准确性和可靠性

Accuracy and reliability of two methods of screening for hypoglycemia in neonates.

作者信息

Ho K L, Loke H L, Tan K W

机构信息

Dept of Neonatal Medicine II, Kandang Kerbau Hospital, Singapore.

出版信息

J Singapore Paediatr Soc. 1991;33(3-4):156-8.

PMID:1812332

Abstract

Two hundred and six neonates were screened for hypoglycemia using two glucose test strips and their results compared with a simultaneous blood sugar obtained from the Beckman's glucose analyser. Both test strips, Reflotest hypoglycemia and the Reflolux (BM test glycemia 20-800) gave rapid estimates of blood sugar readings. In this study, these two strips were assessed in their accuracy and reliability to detect neonatal hypoglycaemia (blood sugar levels less than 2.2 mmol/L). The sensitivity and specificity of the two test strips are 0.82 and 0.90 for Reflotest, and 0.88 and 0.81 for Reflolux respectively. Hence we conclude that both Reflotest and Reflolux are sensitive in detecting blood sugar levels at or below 2.2 mmol/L (40 mg/dl) although Reflolux is less specific. A laboratory result is mandatory before the diagnosis and prognosis of hypoglycemia is made.

摘要

使用两种血糖仪试纸对206名新生儿进行低血糖筛查，并将其结果与同时用贝克曼血糖仪测得的血糖结果进行比较。两种试纸，即Reflotest低血糖试纸和Reflolux（BM血糖检测20 - 800）都能快速得出血糖读数。在本研究中，对这两种试纸检测新生儿低血糖（血糖水平低于2.2 mmol/L）的准确性和可靠性进行了评估。两种试纸的灵敏度和特异性分别为：Reflotest试纸的灵敏度为0.82，特异性为0.90；Reflolux试纸的灵敏度为0.88，特异性为0.81。因此我们得出结论，尽管Reflolux试纸的特异性较低，但Reflotest试纸和Reflolux试纸在检测血糖水平为2.2 mmol/L（40 mg/dl）及以下时都很敏感。在对低血糖进行诊断和预后评估之前，必须要有实验室检测结果。