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[用于检测新生儿低血糖症的新型葡萄糖反射仪(Glucoscot II)的临床评估]

[Clinical assessment of a new glucose reflectance meter (Glucoscot II) for the detection of neonatal hypoglycemias].

作者信息

Leibundgut K E, Bucher H U, Mieth D, Duc G

机构信息

Abteilung für Neonatologie der Universitäts-Frauenklinik Zürich.

出版信息

Monatsschr Kinderheilkd. 1989 Jun;137(6):330-2.

PMID:2761546
Abstract

Glucoscot II, a new glucose reflectance meter and the corresponding test strip "Glucopat" were evaluated for their accuracy in the detection of neonatal hypoglycemia. In 100 neonatal blood samples of 44 neonates glucose was estimated with the reflectance meter and the results were compared with those from a reference method (Beckman-Glucose-Analyser). Hypoglycemia was defined as blood glucose of less than 2.2 mmol/l (40 mg/dl). The correlation between the values obtained by the test strip and the reference values was high (= 0.95). Test sensitivity was 100%, specificity 99% and the predictive value for hypoglycemia was 94%. The incidence of a blood sugar less than 2.2 mmol/l in our study population was 15%. Thirteen percent of glucose values determined with the reflectance meter deviated from the reference value by more then 20%. If our data can be confirmed by others we conclude that the Glucoscot II/Glucopat-system can be recommended as screening-test for hypoglycemia in neonates.

摘要

对新型血糖仪Glucoscot II及其配套试纸“Glucopat”检测新生儿低血糖的准确性进行了评估。在44名新生儿的100份血样中,用该反射式血糖仪测定血糖,并将结果与参考方法(贝克曼葡萄糖分析仪)的结果进行比较。低血糖定义为血糖低于2.2毫摩尔/升(40毫克/分升)。试纸测得的值与参考值之间的相关性很高(=0.95)。检测敏感性为100%,特异性为99%,低血糖的预测值为94%。在我们的研究人群中,血糖低于2.2毫摩尔/升的发生率为15%。用反射式血糖仪测定的血糖值中有13%偏离参考值超过20%。如果我们的数据能得到其他人的证实,我们得出结论,Glucoscot II/Glucopat系统可推荐作为新生儿低血糖的筛查试验。

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