经灭活的分枝杆菌及其他细菌种类对淋巴细胞增殖的刺激作用。
Stimulation of lymphocyte proliferation by killed mycobacteria and other bacterial species.
作者信息
Bekierkunst A
出版信息
Infect Immun. 1976 Jul;14(1):28-32. doi: 10.1128/iai.14.1.28-32.1976.
Abstract
Killed mycobacteria and some mycobacterial fractions induced spleen cells from normal C3H mice to incorporate tritiated thymidine to a relatively high degree. Thymocytes under the same conditions were not activated. However, incorporation of thymidine was significantly increased when mixtures of thymus and spleen cells were cultured in the presence of the inducers. A similar activation of spleen cells was displayed in the presence of gram-positive and gram-negative non-mycobacterial species.
摘要
灭活的分枝杆菌和一些分枝杆菌组分能诱导正常C3H小鼠的脾细胞大量掺入氚标记的胸腺嘧啶核苷。在相同条件下胸腺细胞未被激活。然而，当胸腺细胞和脾细胞的混合物在诱导剂存在的情况下进行培养时，胸腺嘧啶核苷的掺入量显著增加。在革兰氏阳性和革兰氏阴性非分枝杆菌菌种存在的情况下，脾细胞也表现出类似的激活现象。
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