Valdez I H
National Institute of Dental Research, National Institutes of Health, Bethesda 20892.
Spec Care Dentist. 1991 Nov-Dec;11(6):252-5. doi: 10.1111/j.1754-4505.1991.tb01490.x.
Salivary gland dysfunction commonly occurs as a result of radiation therapy for cancers of the head and neck region. The effect of radiation on salivary glands is immediate and predictable. Histologic and sialochemical studies indicate both the acini and ducts are affected. The extent of salivary dysfunction is primarily determined by the radiation field and dose. Radiation-induced salivary dysfunction is permanent and leads to a host of clinical sequelae, both oral and systemic.
唾液腺功能障碍通常是头颈部癌症放射治疗的结果。辐射对唾液腺的影响是即时且可预测的。组织学和唾液化学研究表明，腺泡和导管均受到影响。唾液功能障碍的程度主要由放射野和剂量决定。辐射诱发的唾液功能障碍是永久性的，并会导致一系列口腔和全身的临床后遗症。
