Reuling N, Pohl-Reuling B, Keil M
MZ Zahn-, Mund- und Kieferheilkunde, Philipps-Universität Marburg.
Dtsch Zahnarztl Z. 1991 Mar;46(3):215-9.
The local toxicity (histocompatibility) of 12 dental casting alloys was examined with the aid of quantitative histomorphometry after intramuscular implantation in rabbits. For each alloy examined and each implantation period (2, 4, 8, 12 weeks) two rabbits were used. In each animal eight grooved cylindrical implants of the same alloy were installed in the left paravertebral muscle. Histomorphometric measurements of the thickness of the connective tissue encapsulating the implant were carried out to assess the degree of foreign body reactions caused by the alloys. Histomorphometry revealed significant differences in the thickness of the soft tissue capsule in relation to the length of the implantation period. The study also demonstrated significant differences in capsule thickness for the different dental alloys at equal implantation periods. Quantitative histomorphometry of the thickness of the connective tissue capsule around intramuscularly implanted dental alloys proved to be suitable for examining the histocompatibility of those materials.
在兔子肌肉内植入后，借助定量组织形态计量学对12种牙科铸造合金的局部毒性（组织相容性）进行了检查。对于每种检查的合金和每个植入期（2、4、8、12周），使用了两只兔子。在每只动物的左椎旁肌中植入八个相同合金的带槽圆柱形植入物。对包裹植入物的结缔组织厚度进行组织形态计量学测量，以评估合金引起的异物反应程度。组织形态计量学显示，软组织包膜厚度与植入期长短存在显著差异。该研究还表明，在相同植入期时，不同牙科合金的包膜厚度存在显著差异。肌肉内植入牙科合金周围结缔组织包膜厚度的定量组织形态计量学被证明适用于检查这些材料的组织相容性。
