Ferrari V, Baratelli E, Colombo C, Vitaloni L, Broggini M
Divisione di Medicina generale, Ospedale Filippo Del Ponte, Varese.
Recenti Prog Med. 1991 Dec;82(12):672-4.
Wernicke-Korsakoff's syndrome (W.K.S.) is a complication of alcoholism and malnutrition and usually presents acutely and is characterized by disturbances of consciousness, paralysis of the external ocular muscles, ataxia and disorder of retentive memory. The disease results from deficiency of vitamin B1, or thiamine, an essential coenzyme in intermediate carbohydrate metabolism. We report a seriously ill, nonalcoholic surgical patient, who developed W.K.S. in the postoperative period as a result of thiamine deficiency, during prolonged intravenous therapy. It is recommended that malnourished patients receive 100 mg parenteral thiamine especially when glucose infusions are administered.
韦尼克-科尔萨科夫综合征（W.K.S.）是酒精中毒和营养不良的一种并发症，通常急性发作，其特征为意识障碍、眼外肌麻痹、共济失调和记忆障碍。该疾病是由于维生素B1（即硫胺素）缺乏所致，硫胺素是碳水化合物中间代谢过程中的一种必需辅酶。我们报告了一名病情严重的非酒精性外科手术患者，在长期静脉治疗期间因硫胺素缺乏在术后患上了韦尼克-科尔萨科夫综合征。建议营养不良的患者接受100毫克肠外硫胺素治疗，尤其是在输注葡萄糖时。
