Different patterns of polyadenylation of rhinovirus: specified RNA during multiplication in human aneuploid and diploid cells.
作者信息
Macnaughton M R, Dimmock N J
出版信息
J Gen Virol. 1976 Feb;30(2):263-7. doi: 10.1099/0022-1317-30-2-263.
PMID:181536
Abstract
The polyadenylation of rhinovirus-specified RNA in aneuploid HeLa cells and diploid human embryo lung (HEL) cells has been investigated. Polyadenylation occurs at a faster rate and more extensively to virus-specified RNA in infected HEL cells compared with HeLa cells. Poly(A) is added post-transcriptively in both cell types. Furthermore the addition of adenosine or poly(A) during virus multiplication increases the polyadenylation of virus single-stranded RNAs in both cell types, but to a greater extent in HeLa cells.
摘要
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