鼻病毒多链RNA：复制形式对放线菌素D存在的依赖性。
Rhinovirus multistranded RNA: dependence of the replicative form on the presence of actinomycin D.
作者信息
Macnaughton M R, Cooper J A, Dimmock N J
出版信息
J Virol. 1976 Jun;18(3):926-32. doi: 10.1128/JVI.18.3.926-932.1976.
Abstract
The multistranded and double-stranded RNAs synthesized in HeLa cells infected with rhinovirus in the presence and in the absence of actinomycin D have been characterized by polyacrylamide gel electrophoresis and hybridization studies. The replicative form is only found in infected cells treated with actinomycin D, whereas the replicative intermediate is found in both the presence and the absence of the drug. The significance of these results is discussed.
摘要
通过聚丙烯酰胺凝胶电泳和杂交研究，对在感染鼻病毒的HeLa细胞中，在有和没有放线菌素D的情况下合成的多链和双链RNA进行了表征。复制形式仅在经放线菌素D处理的感染细胞中发现，而复制中间体在有和没有该药物的情况下均能发现。对这些结果的意义进行了讨论。
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