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人胚胎干细胞协作中心:人胚胎干细胞衍生良好操作规范模型的开发

hESCCO: development of good practice models for hES cell derivation.

作者信息

Franklin Sarah B, Hunt Charles, Cornwell Glenda, Peddie Valerie, Desousa Paul, Livie Morag, Stephenson Emma L, Braude Peter R

机构信息

London School of Economics and Political Science, BIOS Centre, Houghton Street, London WC2A 2AE, UK.

出版信息

Regen Med. 2008 Jan;3(1):105-16. doi: 10.2217/17460751.3.1.105.

Abstract

One response of the UK research community to the public sensitivity and logistical complexity of embryo donation to stem cell research has been the formation of a national network of 'human embryonic stem cell coordinators' (hESCCO). The aim of hESCCO is to contribute to the formation and implementation of national standards for hES cell derivation and banking, in particular the ethical protocols for patient information and informed consent. The hESCCO project is an innovative practical intervention within the broader attempt to establish greater transparency, consistency, efficiency and standardization of hES derivation in the UK. A major outcome of the hESCCO initiative has been the drafting and implementation of a national consent form. The lessons learned in this context may be relevant to other practitioners and regulators as a model of best practice in hES cell derivation.

摘要

英国科研界针对公众对胚胎捐赠用于干细胞研究的敏感性以及后勤工作的复杂性所做出的一项回应,是组建了一个由“人类胚胎干细胞协调员”(hESCCO)构成的全国性网络。hESCCO的目标是助力制定并实施人类胚胎干细胞获取与储存的国家标准,尤其是关于患者信息及知情同意的伦理规范。hESCCO项目是在英国为提高人类胚胎干细胞获取的透明度、一致性、效率及标准化而进行的更广泛努力中的一项创新性实际举措。hESCCO倡议的一个主要成果是起草并实施了一份全国性同意书。在此过程中吸取的经验教训,作为人类胚胎干细胞获取方面最佳实践的典范,可能对其他从业者和监管机构具有借鉴意义。

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