三氧化矿物凝聚体而非光固化三氧化矿物凝聚体刺激矿化作用。

Mineral trioxide aggregate but not light-cure mineral trioxide aggregate stimulated mineralization.

作者信息

Gomes-Filho João Eduardo, de Faria Max Dougals, Bernabé Pedro Felício Estrada, Nery Mauro Juvenal, Otoboni-Filho José Arlindo, Dezan-Júnior Eloi, de Moraes Costa Mariana Machado Teixeira, Cannon Mark

机构信息

Department of Endodontics, Araçatuba School of Dentistry-UNESP, Araçatuba, Brazil.

出版信息

J Endod. 2008 Jan;34(1):62-5. doi: 10.1016/j.joen.2007.09.018.

DOI:10.1016/j.joen.2007.09.018

PMID:18155495

Abstract

The purpose of this study was to evaluate the subcutaneous response of rat connective tissue to light-cure MTA and Angelus MTA. These materials were placed in polyethylene and dentin tubes and implanted into dorsal connective tissue of Wistar rats for 30 and 60 days. The specimens were prepared to be stained with hematoxylin-eosin, Von Kossa, and without stain for polarized light and evaluated in an optic microscope. The Angelus MTA showed a mild inflammatory response at 30 days and none at 60 days, characterized by organized connective tissue, presence of some chronic inflammatory cells, and induction of mineralized tissue formation. Light-cure MTA presented a moderate chronic inflammatory response at 30 days that decreased at 60 days but was more intense than with Angelus MTA and without dystrophic calcifications. It was possible to conclude that light-cure MTA was similar to MTA at 60 days, but it did not stimulate mineralization.

摘要

本研究的目的是评估大鼠结缔组织对光固化MTA和安氏MTA的皮下反应。将这些材料置于聚乙烯管和牙本质管中，并植入Wistar大鼠的背部结缔组织中30天和60天。制备标本，用苏木精-伊红、冯·科萨染色，不染色用于偏振光观察，并在光学显微镜下进行评估。安氏MTA在30天时显示出轻度炎症反应，60天时无炎症反应，其特征为结缔组织有序排列、存在一些慢性炎症细胞以及诱导矿化组织形成。光固化MTA在30天时呈现中度慢性炎症反应，60天时有所减轻，但比安氏MTA更强烈，且无营养不良性钙化。可以得出结论，光固化MTA在60天时与MTA相似，但不刺激矿化。