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累及脊柱的儿科肿瘤。

Pediatric tumors involving the spinal column.

作者信息

Sciubba Daniel M, Hsieh Patrick, McLoughlin Gregory S, Jallo George I

机构信息

Department of Neurological Surgery, Johns Hopkins University, Meyer 7-109, 600 North Wolfe Street, Baltimore, MD 21287, USA.

出版信息

Neurosurg Clin N Am. 2008 Jan;19(1):81-92. doi: 10.1016/j.nec.2007.09.008.

Abstract

Primary pediatric spinal column tumors are rare lesions, but they can lead to serious morbidity if left untreated. Progressive pain, deformity, and neurologic decline may result from destructive and compressive insults on neighboring structures. In addition, histologic diagnosis is paramount in determining overall survival and management options. Evolution of spinal instrumentation has allowed safe and effective application of spinal reconstruction to the developing spine. As a result, aggressive surgical decompression, deformity correction, fusion, and gross total tumor resections may improve functional and oncologic outcomes without sacrifice of spinal stability.

摘要

原发性小儿脊柱肿瘤是罕见的病变,但如果不治疗,可能会导致严重的发病率。对邻近结构的破坏和压迫性损伤可能导致进行性疼痛、畸形和神经功能衰退。此外,组织学诊断对于确定总体生存率和治疗方案至关重要。脊柱内固定技术的发展使得脊柱重建能够安全有效地应用于发育中的脊柱。因此,积极的手术减压、畸形矫正、融合和肿瘤全切术可能会改善功能和肿瘤学预后,而不牺牲脊柱稳定性。

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