Bilsky Mark H, Gerszten Peter, Laufer Ilya, Yamada Yoshiya
Department of Neurosurgery, Box 71, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Neurosurg Clin N Am. 2008 Jan;19(1):119-23. doi: 10.1016/j.nec.2007.09.002.
Malignant primary tumors of the spine present difficult management problems because of the complexities of en bloc resection and their chemoresistance and radioresistance. A combination of radiation techniques and advances in systemic therapy may ultimately provide improved local tumor control and cure for these treatment-resistant tumors.
脊柱原发性恶性肿瘤由于整块切除的复杂性以及其化学耐药性和放射抗性,带来了棘手的治疗难题。放射技术与全身治疗进展的结合可能最终为这些难治性肿瘤提供更好的局部肿瘤控制和治愈效果。