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钩端螺旋体病肺出血:一项诊断挑战。

Leptospirosis pulmonary haemorrhage: a diagnostic challenge.

作者信息

Dall'Antonia M, Sluga G, Whitfield S, Teall A, Wilson P, Krahé D

机构信息

Queen Elizabeth Hospital NHS Trust, Stadium Road, Woolwich, London, SE184QH, UK.

出版信息

Emerg Med J. 2008 Jan;25(1):51-2. doi: 10.1136/emj.2007.051524.

Abstract

Leptospirosis is a re-emerging zoonosis with worldwide distribution. Antibiotic treatment is available, but leptospirosis is rarely suspected due to the non-specific clinical presentation, and is also underreported due to the difficulty in confirming the diagnosis. The syndrome of leptospirosis pulmonary haemorrhage is increasingly described; it is severe and can present without the classical manifestations of Weil's disease. We discuss two cases of leptospirosis with pulmonary haemorrhage; both our patients experienced a dramatic deterioration hours after their admission, and required emergency intubation and intensive therapy unit support. Massive haemoptysis is a life threatening complication of leptospirosis, even outside tropical areas.

摘要

钩端螺旋体病是一种再度出现的人畜共患病,在全球范围内均有分布。虽然有抗生素治疗方法,但由于临床表现不具特异性,钩端螺旋体病很少被怀疑,且因诊断困难报告不足。钩端螺旋体病肺出血综合征的描述日益增多;该病病情严重,可能不出现韦尔氏病的典型表现。我们讨论两例钩端螺旋体病伴肺出血的病例;我们的两名患者在入院数小时后病情急剧恶化,需要紧急插管并转入重症监护病房接受支持治疗。即使在热带地区以外,大量咯血也是钩端螺旋体病危及生命的并发症。

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