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[免疫抑制剂环孢素A在牙科领域的副作用]

[Side effects of the immunsuppressive cyclosporin A in dentistry].

作者信息

Braun T, Sponholz F, Sponholz H

机构信息

Medizinischen Fakultät der Universität Rostock.

出版信息

Dtsch Stomatol (1990). 1991;41(4):133-5.

PMID:1815751
Abstract

31 renal transplant patients with Cyclosporin-A-Medication were dental discussed. Half of the patients showed gingival hyperplasia in the anterior region of the maxilla after different time of medication. A relation between gingival hyperplasia, age and sex could'nt be seen. Two stomatitis were presented. The oral hygiene and the parodontal statement before the transplantation influenced the formation of gingival hyperplasia. At time it seems, that Nifedipin has no influence on the formation of gingival hyperplasia. We recommend a extensive research with a long list of patients. A patient with a voluminous hyperplasia was discussed.

摘要

对31例接受环孢素A治疗的肾移植患者进行了牙科讨论。一半患者在用药不同时间后上颌前部出现牙龈增生。未发现牙龈增生与年龄和性别之间存在关联。出现了两例口腔炎。移植前的口腔卫生和牙周状况影响牙龈增生的形成。目前看来,硝苯地平对牙龈增生的形成没有影响。我们建议对大量患者进行广泛研究。讨论了一例牙龈增生严重的患者。

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