Pabinger Ingrid, Eichinger Sabine, Minar Erich, Niessner Herwig
Klinische Abteilung für Hämatologie und Hämostaseologie, Univ.-Klinik für Innere Medizin I, Medizinische Universität Wien, Wien, Osterreich.
Wien Klin Wochenschr. 2007;119(23-24):739-46. doi: 10.1007/s00508-007-0915-z.
Venous thromboembolism occurs in a significant number of patients in typical risk situations (e.g. surgery or trauma). However, in these special high-risk situations anticoagulants, particularly low molecular weight heparin, allow for a decrease in the number of venous thromboses, pulmonary embolisms and deaths caused by pulmonary embolism. Only the wide-spread and adequate use of antithrombotics can safeguard against venous thromboembolism in these various risk situations. Guidelines constitute an integrative part of quality management and ensure the application of evidence-based medicine. The present consensus on thrombosis prophylaxis in Austria has been elaborated by 23 experts in the fields of hemostasis research, angiology, surgery, orthopedics, internal medicine, anaesthesiology and pharmacology. The recommendations for the management of thrombosis prophylaxis in the fields of general surgery, orthopaedic and trauma surgery and internal medicine have been elaborated drawing on the Guidelines issued by the American College of Chest Physicians. Included are recommendations on indications as well as the choice of antithrombotics, dose and duration of therapy for the various conditions. The Austrian Guidelines for Venous Thromboembolism Prophylaxis are meant to be a basis for standardising procedures in the above-mentioned fields, thus contributing to an improved management of risk situations by physicians and health care staff and providing more safety for patients.
在典型风险情况下(如手术或创伤),相当数量的患者会发生静脉血栓栓塞。然而,在这些特殊的高风险情况下,抗凝剂,尤其是低分子量肝素,可减少静脉血栓形成、肺栓塞以及肺栓塞导致的死亡数量。只有广泛且适当地使用抗血栓药物,才能在这些不同风险情况下预防静脉血栓栓塞。指南是质量管理的一个组成部分,可确保循证医学的应用。奥地利目前关于血栓形成预防的共识是由止血研究、血管病学、外科、骨科、内科、麻醉学和药理学领域的23位专家制定的。普通外科、骨科和创伤外科以及内科领域血栓形成预防管理的建议,是根据美国胸科医师学会发布的指南制定的。其中包括针对各种情况的适应证、抗血栓药物选择、治疗剂量和疗程的建议。奥地利静脉血栓栓塞预防指南旨在成为上述领域规范程序的基础,从而有助于医生和医护人员更好地管理风险情况,并为患者提供更多安全保障。