Gehrig Kathryn A, Warshaw Erin M
School of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
J Am Acad Dermatol. 2008 Jan;58(1):1-21. doi: 10.1016/j.jaad.2007.07.050.
Topical antibiotics are widely used to treat cutaneous, ocular, and otic infections. Allergic contact dermatitis to topical antibiotics is a rare but well-documented side effect, especially in at-risk populations. The purpose of this article is to review the epidemiology, responsible allergens, and management of allergic contact dermatitis to topical antibiotics.
After completing this learning activity, participants should be able to describe the epidemiology of allergic contact dermatitis related to topical antibiotics; show knowledge of the most common allergenic topical antibiotics; and understand the allergenic cross-reactivity pattern amongst topical antibiotics.
外用抗生素广泛用于治疗皮肤、眼部和耳部感染。外用抗生素引起的过敏性接触性皮炎是一种罕见但有充分文献记载的副作用，尤其是在高危人群中。本文的目的是综述外用抗生素引起的过敏性接触性皮炎的流行病学、相关过敏原及管理方法。
完成本学习活动后，参与者应能够描述与外用抗生素相关的过敏性接触性皮炎的流行病学；了解最常见的致敏外用抗生素；并理解外用抗生素之间的致敏交叉反应模式。
