Alfieri Roberta, Merelli Ivan, Mosca Ettore, Milanesi Luciano
Istituto di Tecnologie Biomediche-Consiglio Nazionale delle Ricerche, via F.lli Cervi 93, Segrate, Milano, Italy.
Nucleic Acids Res. 2008 Jan;36(Database issue):D641-5. doi: 10.1093/nar/gkm873. Epub 2007 Dec 26.
The cell cycle database is a biological resource that collects the most relevant information related to genes and proteins involved in human and yeast cell cycle processes. The database, which is accessible at the web site http://www.itb.cnr.it/cellcycle, has been developed in a systems biology context, since it also stores the cell cycle mathematical models published in the recent years, with the possibility to simulate them directly. The aim of our resource is to give an exhaustive view of the cell cycle process starting from its building-blocks, genes and proteins, toward the pathway they create, represented by the models.
细胞周期数据库是一种生物资源，它收集了与人类和酵母细胞周期过程中涉及的基因和蛋白质相关的最相关信息。该数据库可在网站http://www.itb.cnr.it/cellcycle上访问，它是在系统生物学背景下开发的，因为它还存储了近年来发表的细胞周期数学模型，并具有直接模拟这些模型的可能性。我们资源的目的是从细胞周期过程的组成部分——基因和蛋白质开始，到它们所创建的由模型表示的途径，全面展示细胞周期过程。
