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地西泮与针灸治疗骨关节炎疼痛的对比研究:一项安慰剂对照研究。

A comparative study of diazepam and acupuncture in patients with osteoarthritis pain: a placebo controlled study.

作者信息

Thomas M, Eriksson S V, Lundeberg T

机构信息

Department of Physiology II, Karolinska Institutet, Stockholm, Sweden.

出版信息

Am J Chin Med. 1991;19(2):95-100. doi: 10.1142/S0192415X91000156.

Abstract

Forty-four patients with chronic cervical osteoarthritis took part in this study. Patients were treated with acupuncture, sham-acupuncture, diazepam or placebo-diazepam in randomized order. Pain was rated on visual analogue scales before, during, and after treatment. Two scales were separately used to rate the intensity (sensory component) and the unpleasantness (affective component) of pain. The results analyzed from these trials show that diazepam, placebo-diazepam, acupuncture and sham-acupuncture have a more pronounced effect on the affective than on the sensory component of pain. Acupuncture was significantly more effective than placebo-diazepam (p less than 0.05), but not significantly more effective than diazepam or sham-acupuncture.

摘要

44例慢性颈椎病患者参与了本研究。患者按随机顺序接受针刺、假针刺、地西泮或安慰剂地西泮治疗。在治疗前、治疗期间和治疗后,采用视觉模拟量表对疼痛进行评分。分别使用两个量表对疼痛的强度(感觉成分)和不愉快程度(情感成分)进行评分。这些试验的分析结果表明,地西泮、安慰剂地西泮、针刺和假针刺对疼痛情感成分的影响比对感觉成分的影响更显著。针刺的效果显著优于安慰剂地西泮(p<0.05),但并不显著优于地西泮或假针刺。

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