Sahani Dushyant V, Shah Zarine K, Catalano Onofrio A, Boland Giles W, Brugge William R
Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
J Gastroenterol Hepatol. 2008 Jan;23(1):23-33. doi: 10.1111/j.1440-1746.2007.05117.x.
Pancreatic adenocarcinoma is one of the leading causes of cancer death in the West, with a poor overall 5-year survival rate of only 4%. Late clinical presentation with an advanced disease results in a low rate of surgical intervention. Tumor serum marker CA 19-9 is sensitive, although not specific for the diagnosis of adenocarcinomas of the pancreas. The treatment approach is based on whether the tumor is resectable or non-resectable at presentation. Therefore, imaging plays a crucial role in the management of this disease. Many modalities are available to image the pancreas. They include non-invasive techniques, like ultrasound, contrast-enhanced multidetector computed tomography, magnetic resonance imaging and integrated positron emission tomography/computed tomography, and invasive techniques, like endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. Each of these modalities has its peculiar strengths and weaknesses.
胰腺腺癌是西方癌症死亡的主要原因之一，总体5年生存率仅为4%，令人沮丧。晚期临床表现及疾病进展导致手术干预率较低。肿瘤血清标志物CA 19-9虽然对胰腺癌的诊断不具有特异性，但具有敏感性。治疗方法取决于肿瘤在初诊时是否可切除。因此，影像学检查在该疾病的管理中起着至关重要的作用。有多种方式可用于胰腺成像。它们包括非侵入性技术，如超声、对比增强多排计算机断层扫描、磁共振成像和正电子发射断层扫描/计算机断层扫描一体化，以及侵入性技术，如内镜逆行胰胆管造影和内镜超声。这些方式中的每一种都有其独特的优缺点。
