Singal Archana, Pandhi Deepika, Bhattacharya Sambit N, Das Shukla, Aggarwal Sarla, Mishra Kiran
Departments of Dermatology and STD, Microbiology, and Pathology, University College of Medical Sciences & GTB Hospital, Delhi, India.
Int J Dermatol. 2008 Jan;47(1):44-7. doi: 10.1111/j.1365-4632.2007.03430.x.
A 10-year-old immunocompetent boy presented with multiple, verrucous, disseminated pheohyphomycotic lesions caused by Exophiala spinifera. The patient was not responsive to combination antifungal therapy (itraconazole, terbinafine, fluconazole) and cryotherapy. As antifungal susceptibility is known to be variable for Exophiala spinifera, in vitro sensitivity testing is recommended before medical treatment. This article reviews, in brief, all cases documented so far in the English literature.
一名10岁免疫功能正常的男孩出现了由棘状外瓶霉引起的多发性、疣状、播散性皮肤暗色丝孢霉病损害。该患者对抗真菌联合治疗(伊曲康唑、特比萘芬、氟康唑)及冷冻治疗均无反应。由于已知棘状外瓶霉的抗真菌药敏性存在差异,因此建议在药物治疗前进行体外药敏试验。本文简要回顾了迄今为止英文文献中记录的所有病例。