巴西南部棘状外瓶霉感染病例：分子鉴定与抗真菌药敏分析
A case of Exophiala spinifera infection in Southern Brazil: Molecular identification and antifungal susceptibility.
作者信息
Daboit Tatiane Caroline, Duquia Rodrigo Pereira, Magagnin Cibele Massotti, Mendes Sandra Denise Camargo, Castrillón Mauricio Ramírez, Steglich Raquel, Dos Santos Inajara Silveira, Vettorato Gerson, Valente Patrícia, Scroferneker Maria Lúcia
机构信息
Graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul. Rua Ramiro Barcelos, 2400 - 2 floor, Porto Alegre, CEP: 90035-003, Brazil ; Department of Microbiology, ICBS, Universidade Federal do Rio Grande do Sul. Rua Sarmento Leite, 500, Sala 210, Porto Alegre, CEP: 90050-170, Brazil.
Dermatology Service, Santa Casa de Misericórdia de Porto Alegre Hospital Complex. Rua Prof. Annes Dias, 285, Porto Alegre, CEP: 90020-090, Brazil.
出版信息
Med Mycol Case Rep. 2012 Sep 7;1(1):72-5. doi: 10.1016/j.mmcr.2012.08.006. eCollection 2012.
Abstract
We report a case of an 80-year-old Brazilian man, farmer, with lesions on the dorsum of the hand. A direct mycological examination, cultivation and microculture slide observation was performed. The sequencing of ITS1-5.8S rDNA-ITS2 region was carried out and the etiological agent confirmed as Exophiala spinifera. The in vitro susceptibility of this isolate to antifungal agents alone and in combination was evaluated. This is the third case of phaeohyphomycosis caused by Exophiala spinifera in Brazil.
摘要
我们报告一例80岁的巴西男性农民病例，其手部背部有皮损。进行了直接真菌学检查、培养及微量培养玻片观察。对ITS1-5.8S rDNA-ITS2区域进行了测序，确认病原体为棘状外瓶霉。评估了该分离株对单一及联合抗真菌药物的体外敏感性。这是巴西第三例由棘状外瓶霉引起的暗色丝孢霉病病例。
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本文引用的文献
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Exophiala spinifera as a cause of cutaneous phaeohyphomycosis: case study and review of the literature.棘状外瓶霉作为皮肤暗色丝孢霉病的病因：病例报告及文献复习
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