Little C J L, Gettinby G
Barton Veterinary Hospital, 34 New Dover Road, Canterbury, CT1 3BH Kent, UK.
J Small Anim Pract. 2008 Jan;49(1):17-25. doi: 10.1111/j.1748-5827.2007.00466.x.
To study the prognosis and cause of death in cats with diabetes mellitus.
Twenty consecutive cases of feline diabetes mellitus diagnosed in first-opinion practice were followed. Three control cats, without diabetes, were matched to each case of diabetes; these were also followed.
One Somali cat with diabetes could not be matched, so complete data analysis considered only 19 diabetics and 57 matched controls. Death occurred in 14 of 20 diabetics and 23 of 57 controls although one control cat was eventually lost to follow-up. Heart disease and heart failure led to death in six diabetic cats. One of these was the non-matched Somali; nevertheless, the death rate from heart disease in the diabetics was five of 19 compared with two of 57 in controls. The relative risk of heart failure in diabetic cats was 10.4 times that of the controls; this difference in rates was statistically significant. Survival amongst diabetics was significantly worse than for controls. For the control cats median survival was 718 days after the index visit, whereas for the diabetic cases median survival was 385 days after diagnosis.
Heart disease and failure are common in diabetic cats. This observation deserves further attention.
研究猫糖尿病的预后及死因。
对首次诊断的20例猫糖尿病连续病例进行随访。为每例糖尿病猫匹配3只无糖尿病的对照猫,同样进行随访。
1只患糖尿病的索马里猫无法匹配,因此完整的数据分析仅纳入19只糖尿病猫和57只匹配的对照猫。20只糖尿病猫中有14只死亡,57只对照猫中有23只死亡,不过有1只对照猫最终失访。6只糖尿病猫死于心脏病和心力衰竭。其中1只是未匹配的索马里猫;尽管如此,糖尿病猫的心脏病死亡率为19只中有5只,而对照猫为57只中有2只。糖尿病猫发生心力衰竭的相对风险是对照猫的10.4倍;这种发生率差异具有统计学意义。糖尿病猫的生存率明显低于对照猫。对照猫在索引访视后的中位生存期为718天,而糖尿病病例在诊断后的中位生存期为385天。
心脏病和心力衰竭在糖尿病猫中很常见。这一观察结果值得进一步关注。