Barrett Kevin M, Brott Thomas G
Department of Neurology-Cannaday 2E, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Curr Atheroscler Rep. 2007 Oct;9(4):333-40. doi: 10.1007/s11883-007-0041-4.
Carotid occlusive disease remains an important cause of ischemic stroke. The results of large, randomized clinical trials have established the benefit of surgical revascularization in selected patients with symptomatic or asymptomatic carotid stenosis. The introduction of balloon angioplasty and stenting of the extracranial carotid artery as a potential alternative to surgery has been received with enthusiasm by patients and physicians alike. Whether or not this enthusiasm is fully justified has yet to be determined. This article reviews published data regarding the safety and clinical efficacy of carotid angioplasty and stenting. Particular focus is directed towards results from recently completed and ongoing prospective comparative trials of endarterectomy and carotid angioplasty and stenting.
颈动脉闭塞性疾病仍然是缺血性中风的一个重要病因。大型随机临床试验的结果已证实,对于有症状或无症状的颈动脉狭窄患者,手术血运重建具有益处。作为手术的一种潜在替代方法,颅外颈动脉球囊血管成形术和支架置入术的引入受到了患者和医生的一致欢迎。这种热情是否完全合理还有待确定。本文回顾了已发表的关于颈动脉血管成形术和支架置入术的安全性及临床疗效的数据。特别关注最近完成的以及正在进行的动脉内膜切除术与颈动脉血管成形术和支架置入术的前瞻性对比试验的结果。