Kim Ju Sun, Yean Min-Hye, Lee Eun-Ju, Jung Hye Sil, Lee Joo Young, Kim Yoon Jung, Kang Sam Sik
Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul, Korea.
Chem Pharm Bull (Tokyo). 2008 Jan;56(1):105-8. doi: 10.1248/cpb.56.105.
Two new cycloartane-type triterpenoid saponins were isolated from the roots of Astragalus membranaceus (FISCH.) BGE. (Leguminosae) cultivated in Kangwon province, Korea. These saponins were named astramembranosides A and B and were established to be cycloastragenol 6,25-di-O-beta-D-glucopyranoside (astramembranoside A) and cyclocanthogenin 3-O-beta-D-glucopyranosyl(1-->2)-beta-D-xylopyranoside (astramembranoside B) on the basis of chemical and spectral evidence. In addition, 12 known saponins were also isolated from the same materials. Although cycloastragenol 3-O-xyloside and agroastragalosides I and II have already been isolated from A. membranaceus adventitious roots, these three saponins together with brachyoside B and azukisaponin V methyl ester were isolated for the first time from this plant.
从韩国江原道种植的膜荚黄芪（豆科）根部分离出两种新的环阿尔廷型三萜皂苷。这些皂苷被命名为膜荚黄芪苷A和B，基于化学和光谱证据确定它们分别为环黄芪醇6,25 - 二 - O - β - D - 吡喃葡萄糖苷（膜荚黄芪苷A）和环刺黄芪皂苷元3 - O - β - D - 吡喃葡萄糖基（1→2）- β - D - 吡喃木糖苷（膜荚黄芪苷B）。此外，还从相同材料中分离出12种已知的皂苷。虽然环黄芪醇3 - O - 木糖苷以及农吉利黄芪皂苷I和II已从膜荚黄芪不定根中分离出来，但这三种皂苷与短柄皂苷B和赤小豆皂苷V甲酯是首次从该植物中分离得到。
