Ito Tsuyoshi, Osawa Susumu, Shibata Hideshi, Kanda Naotoshi
Laboratory of Veterinary Anatomy, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan.
J Vet Med Sci. 2007 Dec;69(12):1277-9. doi: 10.1292/jvms.69.1277.
Mus musculus (M. m.) molossinus has been considered an independent subspecies of Mus musculus. To elucidate the evolutional origin of this subspecies, we carried out double-color FISH using 18s-28s ribosomal DNA and mouse chromosome paint probes. Among eleven rDNA loci detected, five loci on chromosomes 12, 15, 16, 18 and 19 were common to both Mus musculus (M. m.) musculus and M. m. molossinus and the other six loci, on chromosomes 1, 5, 10, 11, 13 and 17, were characteristic in M. m. molossinus. As M. m. molossinus is thought to originate from a hybrid between ancestral colonies of M. m. musculus and Mus musculus castaneus, we supposed that these six rDNA loci might have evolved after geographical isolation of the ancestral hybrid animals from M. m. musculus and M. m. castaneus.
小家鼠（M. m.）琉球亚种一直被视为小家鼠的一个独立亚种。为了阐明该亚种的进化起源，我们使用18s - 28s核糖体DNA和小鼠染色体涂染探针进行了双色荧光原位杂交。在检测到的11个核糖体DNA位点中，12号、15号、16号、18号和19号染色体上的5个位点在小家鼠（M. m.）小家鼠亚种和M. m.琉球亚种中都存在，而1号、5号、10号、11号、13号和17号染色体上的另外6个位点是M. m.琉球亚种所特有的。由于M. m.琉球亚种被认为起源于小家鼠（M. m.）小家鼠亚种和小家鼠栗色亚种的祖先群体之间的杂交后代，我们推测这6个核糖体DNA位点可能是在祖先杂交动物与小家鼠（M. m.）小家鼠亚种和小家鼠栗色亚种地理隔离之后进化而来的。
