Shimada Asuka, Onozato Tomoya, Hoshi Eriko, Togashi Yoshihiko, Matsui Motozumi, Miyake Yoh-Ichi, Kobayashi Yoshiyasu, Furuoka Hidefumi, Matsui Takane, Sasaki Naoki, Ishii Mitsuo, Inokuma Hisashi
Department of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
J Vet Med Sci. 2007 Dec;69(12):1317-9. doi: 10.1292/jvms.69.1317.
An 11-day-old Holstein calf presented with a high rectal temperature and tachypnea. Treatment with antibiotics and non-steroidal anti-inflammatory drugs did not improve the clinical signs. Bleeding tendency, with several hemorrhage spots on the body surface, appeared five days after admission. Severe pancytopenia was observed in the blood examination. The calf died on the 11th day after admission with severe bleeding from an injection site. Necropsy findings revealed that the pancytopenia had resulted from severe bone marrow aplasia. A congenital disorder was suspected to be the cause of pancytopenia associated with bone marrow aplasia.
一头11日龄的荷斯坦犊牛出现直肠温度升高和呼吸急促症状。使用抗生素和非甾体类抗炎药治疗后临床症状并未改善。入院五天后，体表出现多处出血点，呈现出血倾向。血液检查发现严重全血细胞减少。犊牛在入院第11天因注射部位严重出血死亡。尸检结果显示，全血细胞减少是由严重的骨髓发育不全所致。怀疑先天性疾病是导致与骨髓发育不全相关的全血细胞减少的原因。
