Lu Lehui, Ai Kelong, Ozaki Yukihiro
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 130022 Changchun, China.
Langmuir. 2008 Feb 5;24(3):1058-63. doi: 10.1021/la702886q. Epub 2008 Jan 5.
We report a facile and environmentally friendly strategy for high-yield synthesis of highly monodisperse gold nanoparticles with urchin-like shape. A simple protein, gelatin, was first used for the control over shape and orientation of the gold nanoparticles. These nanoparticles, ready to use for biological systems, are promising in the optical imaging-based disease diagnostics and therapy because of their tunable surface plasmon resonance (SPR) and excellent surface-enhanced Raman scattering (SERS) activity.
我们报道了一种简便且环境友好的策略，用于高产率合成具有海胆状形状的高度单分散金纳米颗粒。一种简单的蛋白质——明胶，首先被用于控制金纳米颗粒的形状和取向。这些可直接用于生物系统的纳米颗粒，因其可调谐的表面等离子体共振（SPR）和出色的表面增强拉曼散射（SERS）活性，在基于光学成像的疾病诊断和治疗方面具有广阔前景。
