Erdle Brandon J, Brouxhon Sabine, Kaplan Martin, Vanbuskirk Joanne, Pentland Alice P
Department of Dermatology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.
Dermatol Surg. 2008 Mar;34(3):320-5. doi: 10.1111/j.1524-4725.2007.34065.x. Epub 2007 Dec 20.
Recent work suggests that injuries can heal faster if treated by lasers emitting 670-nm red light. LED lights emitting 670-nm light are now available. This suggests that inexpensive and easy-to-use 670-nm LED lights might help accelerate cutaneous wound healing.
The objective was to evaluate the effect of 670-nm LED light on wound healing in SKH-1 hairless mice.
To study 670-nm light effects on incisional injury, animals were left unexposed or exposed to equal doses of high-, medium-, or low-flux light. Burn injuries were treated with high-flux light or left unexposed. Healing was assessed by measurement of the burn area and the gap remaining to closure of incisional injury.
Mice exposed to 670-nm red light showed significantly faster healing than control mice. High, medium, and low fluxes of light were all effective after incisional injury. In burn injury, there was improvement in wound healing initially, but the time to repair was unchanged.
A 670-nm LED red light source accelerates healing in skin of SKH-1 hairless mice after incisional injuries, but is not as effective for burn injuries. These data that suggest red light exposure may be helpful in postoperative wound repair.
近期研究表明，用发射670纳米红光的激光进行治疗，伤口愈合速度可能会更快。目前已有发射670纳米光的发光二极管（LED）灯。这表明，价格低廉且易于使用的670纳米LED灯可能有助于加速皮肤伤口愈合。
评估670纳米LED灯对SKH-1无毛小鼠伤口愈合的影响。
为研究670纳米光对切口损伤的影响，将动物分为未暴露组以及暴露于等剂量高、中、低通量光的组。烧伤损伤用高通量光治疗或不进行处理。通过测量烧伤面积和切口损伤闭合剩余间隙来评估愈合情况。
暴露于670纳米红光的小鼠愈合速度明显快于对照小鼠。切口损伤后，高、中、低通量的光均有效。在烧伤损伤中，伤口愈合最初有改善，但修复时间未变。
670纳米LED红光源可加速SKH-1无毛小鼠切口损伤后皮肤的愈合，但对烧伤损伤效果不佳。这些数据表明红光照射可能有助于术后伤口修复。
