全脑缺氧时的韦尼克脑病样病变

Wernicke's encephalopathy-like lesions in global cerebral hypoxia.

作者信息

Johkura Ken, Naito Makoto

机构信息

Department of Neurology, Hiratsuka Kyosai Hospital, 9-11 Oiwake, Hiratsuka 254-8502, Kanagawa, Japan.

出版信息

J Clin Neurosci. 2008 Mar;15(3):318-9. doi: 10.1016/j.jocn.2006.10.022.

DOI:10.1016/j.jocn.2006.10.022

PMID:18178437

Abstract

We report a patient with severe hypoxic encephalopathy after cardiac arrest, in which lesions depicted on MRI involved mainly the periaqueductal brainstem, hypothalamus and mamillary bodies, and medial thalami. Hypoxia usually causes cerebro-cerebellar cortical damage. However, it may also cause midline lesions of similar distribution to those of Wernicke's encephalopathy due to thiamine deficiency.

摘要

我们报告了一例心脏骤停后发生严重缺氧性脑病的患者，其MRI显示的病变主要累及中脑导水管周围脑干、下丘脑、乳头体及丘脑内侧。缺氧通常会导致大脑和小脑皮质损伤。然而，它也可能由于硫胺素缺乏而导致与韦尼克脑病分布相似的中线病变。