Ferris Daron G, Waller Jennifer L, Owen Ashley, Smith Jozette
Gynecologic Prevention Center, Department of Family Medicine, Medical College of Georgia, Augusta, GA 30912, USA.
J Am Board Fam Med. 2008 Jan-Feb;21(1):31-7. doi: 10.3122/jabfm.2008.01.070103.
To determine correlates of human papillomavirus (HPV) vaccine acceptance in mid-adult women.
A convenience sample of 472 mid-adult women completed a 2-part, 69-item survey that included demographic, knowledge, and behavioral variables as potential correlates of vaccine acceptance. Univariable and multivariable logistic regression models were used to identify correlates for vaccine acceptance.
Mid-adult women who received the HPV vaccine were more likely to be younger than 55 years (P < .001); have had an abnormal Papanicolaou test (odds ratio [OR], 2.15; 95% CI, 1.18-3.92); understand that HPV causes cervical cancer (OR, 2.39; 95% CI, 1.08-5.30); feel at risk for HPV infection (OR, 2.14; 95% CI, 1.00-4.57), and feel it is important for their partner (OR, 25.20; 95% CI, 9.66-65.72) and children (OR, 3.54; CI, 0.51-24.56) to get the HPV vaccine. Monogamous mid-adult women (OR, 0.46; 95% CI, 0.21-1.00); women who did not want any vaccines (OR, 0.26; 95% CI, 0.07-0.92); and women who felt it was too late to get the vaccine (OR, 0.18; 95% CI, 0.08-0.44) were less likely to want the HPV vaccine.
These clinical predictors of HPV vaccine acceptance will help clinicians recognize mid-adult women who may be more receptive to vaccination.
确定中年女性对人乳头瘤病毒(HPV)疫苗接受情况的相关因素。
选取472名中年女性组成便利样本,她们完成了一项由两部分组成、共69项的调查,内容包括人口统计学、知识及行为变量,这些均为疫苗接受情况的潜在相关因素。采用单变量和多变量逻辑回归模型来确定疫苗接受情况的相关因素。
接种HPV疫苗的中年女性更可能年龄小于55岁(P < .001);曾有巴氏试验异常(比值比[OR],2.15;95%置信区间[CI],1.18 - 3.92);了解HPV可导致宫颈癌(OR,2.39;95% CI,1.08 - 5.30);感觉有感染HPV的风险(OR,2.14;95% CI,1.00 - 4.57),并且认为HPV疫苗对其伴侣(OR,25.20;95% CI,9.66 - 65.72)和子女(OR,3.54;CI,0.51 - 24.56)很重要。实行一夫一妻制的中年女性(OR,0.46;95% CI,0.21 - 1.00);不想要任何疫苗的女性(OR,0.26;95% CI,0.07 - 0.92);以及认为接种疫苗为时已晚的女性(OR,0.18;95% CI,0.08 - 0.44)接受HPV疫苗的可能性较小。
这些HPV疫苗接受情况的临床预测因素将有助于临床医生识别可能更愿意接受疫苗接种的中年女性。