一项目标导向康复计划对轻度认知障碍的影响：一项试点研究。
Effects of a goal-oriented rehabilitation program in mild cognitive impairment: a pilot study.
作者信息
Londos E, Boschian K, Lindén A, Persson C, Minthon L, Lexell J
机构信息
Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden.
出版信息
Am J Alzheimers Dis Other Demen. 2008 Apr-May;23(2):177-83. doi: 10.1177/1533317507312622. Epub 2008 Jan 8.
BACKGROUND
Memory disturbance, deficient concentration, and fatigue are symptoms seen in amnestic mild cognitive impairment (MCI) as well as in mild traumatic brain injury (TBI). The aim of this study was to assess if an established rehabilitation program commonly used in TBI can aid MCI patients to develop compensatory memory strategies that can improve their cognition, occupational performance, and quality of life (QoL).
METHODS
Fifteen patients with MCI participated in the program 2 days per week for 8 weeks. Cognitive function, occupational performance, and self-perceived QoL were assessed at baseline, at the end of the intervention, and at follow-up after 6 months.
RESULTS
Significant improvements were seen in cognitive processing speed, occupational performance, and in some of the QoL domains.
CONCLUSION
As this goal-oriented rehabilitation program in MCI resulted in some improvements in cognition, occupational performance, and QoL, further randomized controlled studies are warranted.
背景
记忆障碍、注意力不集中和疲劳是遗忘型轻度认知障碍（MCI）以及轻度创伤性脑损伤（TBI）中出现的症状。本研究的目的是评估一种常用于TBI的既定康复方案是否能帮助MCI患者制定补偿性记忆策略，从而改善他们的认知、职业表现和生活质量（QoL）。
方法
15名MCI患者每周参加2天该方案，为期8周。在基线、干预结束时以及6个月后的随访中评估认知功能、职业表现和自我感知的生活质量。
结果
在认知处理速度、职业表现以及一些生活质量领域均有显著改善。
结论
由于MCI中这种以目标为导向的康复方案在认知、职业表现和生活质量方面带来了一些改善，因此有必要进行进一步的随机对照研究。
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