Talassi E, Guerreschi M, Feriani M, Fedi V, Bianchetti A, Trabucchi M
Istituto Clinico S. Anna Hospital, Brescia, Italy.
Arch Gerontol Geriatr. 2007;44 Suppl 1:391-9. doi: 10.1016/j.archger.2007.01.055.
Data support the evidence that neuropsychological rehabilitation is effective in Alzheimer disease (AD), to strengthen the pharmacological treatment to delay the progression of dementia. At moment, a few studies have examined the efficacy of non-pharmacological treatment in MCI. This is a controlled study that assesses the effectiveness of neuropsychological rehabilitation on cognitive and behavioral symptoms and functional status in a group of community-dwelling subjects with MCI and MD. Our results demonstrate that a systematic rehabilitation, that provides a computerized cognitive program training, produces an improvement in cognitive and affective status of patients with MCI and MD, while a rehabilitation program not providing a punctual stimulation of cognitive functions, does not have significant effects.
数据支持神经心理康复对阿尔茨海默病（AD）有效的证据，以加强药物治疗来延缓痴呆症的进展。目前，很少有研究考察非药物治疗对轻度认知障碍（MCI）的疗效。这是一项对照研究，评估神经心理康复对一组患有MCI和轻度抑郁（MD）的社区居住受试者的认知和行为症状及功能状态的有效性。我们的结果表明，提供计算机化认知程序训练的系统性康复能改善MCI和MD患者的认知和情感状态，而不提供针对性认知功能刺激的康复项目则没有显著效果。
