Gelos Marcos, Behringer Dirk, Philippou Stathis, Mann Benno
Department of General and Visceral Surgery, Augusta-Kranken-Anstalt, Bochum, Germany.
JOP. 2008 Jan 8;9(1):50-5.
Carcinosarcoma (malignant mixed tumor) is a rare variant of a pancreatic neoplasm having a dismal prognosis; very few clinical data and treatment options have been published. Unlike adenocarcinoma of the pancreas, there is nothing specific in the literature for this variant regarding postoperative treatment with chemotherapeutic agents.
We report the case of a 61-year-old woman presenting with anemia. Examination revealed a mass in the pancreatic head and she underwent a partial pancreaticoduodenectomy. Histopathological examination revealed a pancreatic neoplasm with both adenomatous as well as sarcomatous characteristics. Postoperatively, the patient was treated with gemcitabine and was in a good health for 9 months. Three follow-up CT scans were done, showing complete remission. Eleven months postoperatively, the patient died from a recurrence.
Carcinosarcoma of the pancreas is a very rare disease having a dismal prognosis. In addition to reviewing the literature on this entity, we present the first published case where gemcitabine was administered as a treatment modality in combination with surgery.
癌肉瘤（恶性混合瘤）是胰腺肿瘤的一种罕见变体，预后不佳；已发表的临床数据和治疗选择非常少。与胰腺腺癌不同，关于这种变体使用化疗药物进行术后治疗，文献中没有具体内容。
我们报告一例61岁女性，因贫血就诊。检查发现胰头有肿块，她接受了胰十二指肠部分切除术。组织病理学检查显示胰腺肿瘤具有腺瘤样和肉瘤样特征。术后，患者接受吉西他滨治疗，健康状况良好达9个月。进行了三次随访CT扫描，显示完全缓解。术后11个月时，患者因复发死亡。
胰腺癌肉瘤是一种非常罕见的疾病，预后不佳。除了回顾关于该实体的文献外，我们还呈现了首例已发表的病例，即吉西他滨作为一种治疗方式与手术联合使用。
